The Serie A champions beat Barca by the same scoreline in the quarter-finals last season before holding out for a second-leg stalemate at Camp Nou.
Lionel Messi netted a brilliant brace as Barcelona helped themselves to a dose of Champions League revenge with a dominant 3-0 Group D win over Juventus.
Barca have since lost Neymar to Paris Saint-Germain, but it was Juve’s’ most notable pre-season departure – Leonardo Bonucci’s surprise switch to AC Milan – that loomed largest over this match as a once formidable defence was cut to ribbons in Giorgio Chiellini’s injury absence.
Record signing Ousmane Dembele was busy on his full Barca debut, but it was a more familiar face that thrilled the home crowd.
Messi’s magnificent opener in the final minute of the opening 45 marked the first time he has scored against fellow all-time great Gianluigi Buffon in the Juventus goal.
After making the second for Ivan Rakitic he repeated the trick to seal the points and maintain Barca’s resurgent early season form under Ernesto Valverde.